Spironolactone Clears Up the Acne I Get From My IUD

By Sophie Vershbow and Micaela Mackenzie
September 15, 2022 - Allure

“Like many people with uteruses, I was first prescribed spironolactone after getting an IUD (Mirena) implanted in 2018. 

Right before my OBGYN shoved a piece of plastic into my cervix, she said to let her know if I started breaking out. Lo and behold, angry cysts cropped up on my face six weeks later, leaving me self-conscious in a way that I hadn't felt since high school. My OBGYN wrote me a prescription for spironolactone and within a few months, my skin was clearer than it had been before the IUD. “

With a huge increase in people with uteruses seeking long lasting birth control in the wake of the Roe reversal, demand for IUDs has gone up. A survey conducted by the Harris Poll on behalf of TIME magazine in July found that 21 percent of women "reported changing their primary contraception method" since the June 24 ruling. Seventeen percent of those surveyed said their primary method of birth control was an IUD or implant. 

“So it's not hard to imagine an increased demand for spironolactone, either. That's because "hormonal IUDs like Mirena, Skyla, and Liletta have been associated with worsening acne, particularly for those who breakout before their period," Dr. Shao adds. "Some suggest that this occurs mostly in patients who have switched from a birth control pill to an IUD (since the birth control pill had been helping to control acne symptoms). Others suggest that the IUD itself may worsen acne due to the hormone progestin that is released."“